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Guinea/ Guinée

Modelling the evolution of transmission of gHAT in Guinea

Graphical abstract for the article "evolution and impact of the strategy to eliminate gHAT in Guinea". Is shows a map of the location of the endemic foci in Guinea, a timeline of cases of gHAT in Guinea for 2000 to 2024 with vector control starting in 2012, rapid tests being introduced in 2014 and the Ebola outbreak during 2014-2016. Other images include the model estimated reducion in new transmission events under the actual scenario and also counterfactual scenarios without Ebola, rapid tests or vector control.

Using the data from the national programme in Guinea coupled with the ¹û¶³´«Ã½ gHAT model, we estimated the reduction in gHAT transmission for the remaining foci in Guinea between 2000 and 2024. Despite variable case reporting in this period, we estimated an overall decrease in transmission, particularly thanks to the introduction of vector control, starting initially in 2012. Unsurprisingly, Ebola increased the disease burden due to gHAT by restricting medical activities, whilst the introduction of new diagnostic tests reduced disease burden and transmission. The modelling highlights the great success of the combined medical and entomological activities against gHAT over the past 25 years, however, continued efforts will be needed to move from very low to zero case reporting.

Pre-print paper: Kagbadouno M, Crump RC, Sutherland SA, Sunnucks R, Camara O, Huang C, Diallo MB, Camara M, Béavogui F, Camara D, Allain K, Brown PEC, Diaby A, Bucheton B, Bessell PR, Crowley EH, Bart J-M, Rock KR, Camara M (2026). MedRxiv. French main textLink opens in a new window.

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