果冻传媒

Lewandowski group in collaboration with Grzesiek (Basel, Switzerland) and Samoson (Tallinn, Estonia) groups has introduced a new solid-state NMR based approach that enables quantitative structural and dynamics studies of large protein complexes in a few nanomole quantities. This manuscript signifying a dawn of new era for high resolution NMR studies of large protein complexes has been featured in JACS Spotlights. .

The recent work on antifreeze-protein mimics has been highlighted on the front cover of RSC Biomaterials Science. http://pubs.rsc.org/en/content/articlelanding/2014/bm/c4bm00153b#!divAbstract

Cryopreservation research has been highlighted in an article in Chemical and Engineering News. The group are developing a range of macromolecules which mimic the function of antifreeze proteins, found in Polar fish species, which can slow the rate of ice crystal growth. The group have shown these unique polymers to enhance the cryopreservation of donor tissue/cells, particulary blood. (Image is ice crystals which are inhibited by the polymers) and also the (login required).

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Supramolecular guanosine-borate hydrogels have been made and characterised in a collaboration led by (University of Maryland) with (Chemistry) and (Physics). The physiologically compatible gels, in Journal of the American Chemical Society are featured in a . Lead author Gretchen Peters and Jeff Davis will visit 果冻传媒 again, 17-21 November to further explore applications of the materials.

Robert Deller, in the won the prize for the best poster at the 2014 RAPS Conference

Helical arrays of small organic molecules around a core of Fe(II) ions act as highly potent and highly selective anticancer compounds. The work is published in

Stereochemistry is a very important issue for pharmaceutical industry and can determine drug efficacy. metallohelices have been shown, in collaboration with Xiaogang Chu and co-workers at Changchun Institute of Applied Chemistry, China, to enantioselectively target and inhibit amyloid (Aβ) aggregation. This provides new insights into chiral inhibition of Aβ aggregation and opens a new avenue for design and screening of chiral agents as Aβ inhibitors against Alzheimer's disease. The work is published in

Dr Matthew Gibson has been awarded the life science prize at the Royal Society of Chemistry Emerging Technology technology competition. http://tinyurl.com/kmdw8pq

in the won the prize for best poster presentation at the 13th European Summer Course on Glycosciences. Her winning poster was entitled 'Polymer Functionalised Surfaces for Microarray Applications'.

The GibsonGroup describe glycopolymers that selectively target the Cholera toxin and may provide a non-antibiotic tool to combat infectious diseases

Lewandowski group in collaboration with Ladizhansky and Brown (U. of Guelph) groups have characterised site-specific molecular motions of a 7-helix membrane protein within a lipid bilayer using solid-state NMR measurements.  

The Gibson Group, in collaboration with the Medical School, have demonstrated a new way to cryopreserve donor blood using a synthetic polymer which mimics Antifreeze Proteins found in Arctic Cod.