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About the event

This meeting is motivated by shared research interests between the Centre for Mechanochemical Cell Biology at ¹û¶³´«Ã½ and the Laboratory for Molecular Cell Biology at UCL. However, the meeting is open to other interested researchers, especially ECRs.

Organisers: Associate Prof Timothy Saunders (¹û¶³´«Ã½) and Prof Yanlan Mao (UCL)

Location: Interdisciplinary Biomedical Research Building (IBRB) Gibbet Hill Campus, ¹û¶³´«Ã½

Forming specific cellular and tissue shapes is a multi-scale process. Processes from the molecular scale through to tissue scale are critical in ensuring robust morphogenesis. Further, it is becoming increasingly apparent that understanding when processes occur is critical in generating specific biological shape. This also makes the importance of integrating modelling clear; biophysical and mathematical modelling provides a powerful framework for understanding how processes occurring across multiple scales can impact on morphogenesis.

This meeting will have plenty of time provided for questions and interactions between researchers working at different levels of detail and with differing approaches.

Key questions include:

• How do subcellular scale processes shape cells and tissues?
• Different molecular processes occur across a broad range of time scales. What role does temporal coordination play in precise organ formation?
• Is there feedback from tissue scale processes back to subcellular levels – e.g., in gene regulation? Such mechanotransduction could be important in robust organogenesis.